Preimplantation Genetic Testing (PGT-A)
Advanced next-generation DNA sequencing of embryos prior to transfer to identify chromosomal abnormalities, reduce miscarriage, and improve IVF success.
99%+
Reduced
Day 5/6
NGS
Understanding the Procedure & Clinical Approach
Preimplantation Genetic Testing for Aneuploidies (PGT-A) is an advanced genetic screening tool used during an IVF cycle. By analyzing the 23 pairs of chromosomes in an embryo before it is transferred, PGT-A identifies which embryos are chromosomally normal (euploid) versus abnormal (aneuploid).
Transferring a euploid embryo significantly enhances implantation rates, shortens the time to pregnancy, and dramatically reduces the risk of early miscarriage.
Step-by-Step Treatment Protocol
Blastocyst Development
Embryos are cultured in our lab to the Day 5 or Day 6 blastocyst stage comprising over 100 cells.
Laser-Assisted Micro-Biopsy
An expert embryologist uses a non-contact laser to sample 4-6 cells from the trophectoderm (outer cell layer), leaving the inner cell mass untouched.
Vitrification & DNA Sequencing
The biopsied embryos are safely frozen via vitrification while sample DNA is amplified and analyzed using Next-Generation Sequencing (NGS).
Targeted Euploid Transfer
A single genetically normal embryo is thawed and transferred into a prepared uterus in a subsequent Frozen Embryo Transfer cycle.
Who is an Ideal Candidate?
- ✓ Women aged 35 and older undergoing IVF
- ✓ History of recurrent miscarriages (recurrent pregnancy loss)
- ✓ Previous unsuccessful IVF cycles with good-quality morphological embryos
- ✓ Couples seeking single embryo transfer with highest success probability
- ✓ Severe male factor infertility associated with chromosomal aneuploidy
Frequently Asked Questions
Does embryo biopsy harm the baby?
No. Biopsy samples are taken solely from the trophectoderm (which forms the placenta), leaving the inner cell mass (which develops into the baby) completely intact and unharmed.
How long do PGT-A results take?
Genetic sequencing reports are typically delivered within 10 to 14 days, allowing ample time to prepare the uterus for a frozen transfer.
Quick Treatment Facts
Timeline: Integrated with IVF & FET
Hospital Stay: Laboratory Screening
Location: Ramesh Hospitals, Ongole
Ready to discuss PGT-A Testing?
Take the first step with confidence. Book your consultation with Dr. Prathima Kamisetty at Komali Fertility Centre Ongole.