What is Vitrification?
Traditional slow-freezing methods carried a risk of ice crystal formation, which could damage delicate cellular membranes. Modern fertility centres utilize vitrification — an ultra-rapid cooling technique that lowers temperatures by up to 20,000°C per minute.
This instantaneous transition transforms intracellular liquid into a smooth, glass-like state without any crystal formation, achieving post-thaw survival rates consistently exceeding 95%.
Egg Freezing vs. Embryo Freezing
While embryos contain robust multi-cell structures that withstand freezing exceptionally well, unfertilized oocytes (eggs) are larger single cells with higher water content. With specialized cryoprotectants and vitrification protocols, egg freezing now achieves clinical pregnancy success rates comparable to fresh cycles.
Who Benefits Most from Cryopreservation?
- Elective Fertility Preservation: Women choosing to freeze mature eggs in their 20s or early 30s to pause biological aging.
- IVF Cycle Optimization: Freezing high-grade blastocysts for a Frozen Embryo Transfer (FET) cycle, allowing the uterine lining to recover in a natural hormonal environment.
- Medical Indications: Preserving reproductive tissue prior to medical treatments or surgeries.
“At Komali Fertility Centre, our goal is to empower every individual and couple with transparent medical knowledge, compassionate guidance, and clinical excellence at every step.”
— Dr. Prathima Kamisetty, Medical Director